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A miRNA screen procedure identifies garz as an essential factor in adult glia functions and validates Drosophila as a beneficial 3Rs model to study glial functions and GBF1 biology
Invertebrate glia performs most of the key functions controlled by mammalian glia in the nervous system and provides an ideal model for genetic studies of glial functions. To study the influence of adult glial cells in ageing we have performed a genetic screen in Drosophila using a collection of tra...
Autores principales: | Gonçalves-Pimentel, Catarina, Mazaud, David, Kottler, Benjamin, Proelss, Sandra, Hirth, Frank, Fanto, Manolis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309417/ https://www.ncbi.nlm.nih.gov/pubmed/32595956 http://dx.doi.org/10.12688/f1000research.23154.2 |
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