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ABC transporters and the hallmarks of cancer: roles in cancer aggressiveness beyond multidrug resistance

The ATP-binding cassette transporters (ABC transporters) have been intensely studied over the past 50 years for their involvement in the multidrug resistance (MDR) phenotype, especially in cancer. They are frequently overexpressed in both naive and post-treatment tumors, and hinder effective chemoth...

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Detalles Bibliográficos
Autores principales:	Muriithi, Wanjiru, Macharia, Lucy Wanjiku, Heming, Carlos Pilotto, Echevarria, Juliana Lima, Nyachieo, Atunga, Filho, Paulo Niemeyer, Neto, Vivaldo Moura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Compuscript 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309456/ https://www.ncbi.nlm.nih.gov/pubmed/32587767 http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0284

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