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TNF‐α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury

OBJECTIVE: Acute kidney injury (AKI) is a common complication of acute liver failure (ALF). Pyroptosis is a necrosis type related to inflammation. This study aimed to investigate the role of TNF‐α/HMGB1 pathway in pyroptosis during ALF and AKI. METHODS: An ALF and AKI mouse model was generated using...

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Detalles Bibliográficos
Autores principales:	Wang, Yao, Zhang, Haiyue, Chen, Qian, Jiao, Fangzhou, Shi, Chunxia, Pei, Maohua, Lv, Jian, Zhang, Hong, Wang, Luwen, Gong, Zuojiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309595/ https://www.ncbi.nlm.nih.gov/pubmed/32419317 http://dx.doi.org/10.1111/cpr.12829

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