Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer’s Disease

Donepezil (DPZ) is an acetylcholinesterase inhibitor used in Alzheimer’s disease to restore cognitive functions but is endowed with limited efficacy. Recent studies pointed out the implication of astroglial networks in cognitive processes, notably via astrocyte connexins (Cxs), proteins involved in...

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Detalles Bibliográficos
Autores principales: Droguerre, Marine, Duchêne, Adeline, Picoli, Christèle, Portal, Benjamin, Lejards, Camille, Guiard, Bruno P., Meunier, Johann, Villard, Vanessa, Déglon, Nicole, Hamon, Michel, Mouthon, Franck, Charvériat, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309601/
https://www.ncbi.nlm.nih.gov/pubmed/32612499
http://dx.doi.org/10.3389/fnins.2020.00563

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