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Olfactory and gustatory abnormalities in COVID-19 cases

PURPOSE: At the time of writing, there is a pandemic affecting virtually every country on Earth. There is considerable discussion amongst clinicians as well as lay people about anosmia and ageusia in COVID-19 sufferers. We aimed to report the results from comprehensive olfactory and gustatory testin...

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Autores principales: Altin, Fazilet, Cingi, Cemal, Uzun, Tankut, Bal, Cengiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309687/
https://www.ncbi.nlm.nih.gov/pubmed/32577902
http://dx.doi.org/10.1007/s00405-020-06155-9
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author Altin, Fazilet
Cingi, Cemal
Uzun, Tankut
Bal, Cengiz
author_facet Altin, Fazilet
Cingi, Cemal
Uzun, Tankut
Bal, Cengiz
author_sort Altin, Fazilet
collection PubMed
description PURPOSE: At the time of writing, there is a pandemic affecting virtually every country on Earth. There is considerable discussion amongst clinicians as well as lay people about anosmia and ageusia in COVID-19 sufferers. We aimed to report the results from comprehensive olfactory and gustatory testing in a series of hospital in-patients. METHODS: The prospective study evaluated 81 individuals with a COVID-19 infection, as confirmed by 2019 n-cov Real-Time PCR laboratory testing. The control group consisted of forty individuals with COVID-19 negative. Olfactory and gustatory testings were carried out by an examiner utilizing stringent safety standards and wearing full personal protective equipment. The results obtained in the case group were then compared with those obtained for the controls. RESULTS: In the case group, 41(50.6%) of patients were male and 40 (49.4%) were female, mean age of 54.16 ± 16.98 years (18–95). In the control group, 21 (52.5%) of subjects were male and 19 (47.5%) were female, and mean age was 55 ± 15.39 years (18–90). Fifty (61.7%) COVID-19-positive patients had complaints related to olfaction. The distribution of olfactory symptoms in the case group differed at the level of statistical significance from the control group (p < 0.001). Turning to gustatory abnormalities, within the case group, 22 individuals (27.2%) had taste malfunction. A statistically significant difference was found in the distribution of gustatory abnormalities between cases and controls (p < 0.001). CONCLUSIONS: Olfactory and gustatory dysfunctions are strongly associated with SARS-CoV-2 infection. Hyposmia with or without hypogeusia is potentially a reliable indicator of latent COVID-19.
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spelling pubmed-73096872020-06-23 Olfactory and gustatory abnormalities in COVID-19 cases Altin, Fazilet Cingi, Cemal Uzun, Tankut Bal, Cengiz Eur Arch Otorhinolaryngol Rhinology PURPOSE: At the time of writing, there is a pandemic affecting virtually every country on Earth. There is considerable discussion amongst clinicians as well as lay people about anosmia and ageusia in COVID-19 sufferers. We aimed to report the results from comprehensive olfactory and gustatory testing in a series of hospital in-patients. METHODS: The prospective study evaluated 81 individuals with a COVID-19 infection, as confirmed by 2019 n-cov Real-Time PCR laboratory testing. The control group consisted of forty individuals with COVID-19 negative. Olfactory and gustatory testings were carried out by an examiner utilizing stringent safety standards and wearing full personal protective equipment. The results obtained in the case group were then compared with those obtained for the controls. RESULTS: In the case group, 41(50.6%) of patients were male and 40 (49.4%) were female, mean age of 54.16 ± 16.98 years (18–95). In the control group, 21 (52.5%) of subjects were male and 19 (47.5%) were female, and mean age was 55 ± 15.39 years (18–90). Fifty (61.7%) COVID-19-positive patients had complaints related to olfaction. The distribution of olfactory symptoms in the case group differed at the level of statistical significance from the control group (p < 0.001). Turning to gustatory abnormalities, within the case group, 22 individuals (27.2%) had taste malfunction. A statistically significant difference was found in the distribution of gustatory abnormalities between cases and controls (p < 0.001). CONCLUSIONS: Olfactory and gustatory dysfunctions are strongly associated with SARS-CoV-2 infection. Hyposmia with or without hypogeusia is potentially a reliable indicator of latent COVID-19. Springer Berlin Heidelberg 2020-06-23 2020 /pmc/articles/PMC7309687/ /pubmed/32577902 http://dx.doi.org/10.1007/s00405-020-06155-9 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Rhinology
Altin, Fazilet
Cingi, Cemal
Uzun, Tankut
Bal, Cengiz
Olfactory and gustatory abnormalities in COVID-19 cases
title Olfactory and gustatory abnormalities in COVID-19 cases
title_full Olfactory and gustatory abnormalities in COVID-19 cases
title_fullStr Olfactory and gustatory abnormalities in COVID-19 cases
title_full_unstemmed Olfactory and gustatory abnormalities in COVID-19 cases
title_short Olfactory and gustatory abnormalities in COVID-19 cases
title_sort olfactory and gustatory abnormalities in covid-19 cases
topic Rhinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309687/
https://www.ncbi.nlm.nih.gov/pubmed/32577902
http://dx.doi.org/10.1007/s00405-020-06155-9
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AT balcengiz olfactoryandgustatoryabnormalitiesincovid19cases