Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

BACKGROUND: DNA methylation is a well-studied epigenetic mark that is frequently altered in diseases such as cancer, where specific changes are known to reflect the type and severity of the disease. Therefore, there is a growing interest in assessing the clinical utility of DNA methylation as a biom...

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Detalles Bibliográficos
Autores principales: Lam, Dilys, Luu, Phuc-Loi, Song, Jenny Z., Qu, Wenjia, Risbridger, Gail P., Lawrence, Mitchell G., Lu, Jennifer, Trau, Matt, Korbie, Darren, Clark, Susan J., Pidsley, Ruth, Stirzaker, Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310104/
https://www.ncbi.nlm.nih.gov/pubmed/32571390
http://dx.doi.org/10.1186/s13148-020-00880-y

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