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Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma

BACKGROUND: The clinical significance of GLI1 expression either through canonical Hedgehog signal transduction or through non-canonical mechanisms in rhabdomyosarcoma (RMS) or Ewing sarcoma (EWS) is incompletely understood. We tested a role for Hedgehog (HH) signal transduction and GL11 expression i...

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Detalles Bibliográficos
Autores principales:	Yoon, Joon Won, Lamm, Marilyn, Chandler, Christopher, Iannaccone, Philip, Walterhouse, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310145/ https://www.ncbi.nlm.nih.gov/pubmed/32493277 http://dx.doi.org/10.1186/s12885-020-06985-0

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