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Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer
BACKGROUND: As a natural alkaloid product isolated from Sophora alopecuroides. L, Sophoridine reshapes gastric cancer immune microenvironment via inhibiting chemotaxis and M2 polarization of tumor-associated macrophages (TAMs). However, the exact effects and underlying mechanism of Sophoridine on ga...
Autores principales: | Peng, Zhiyang, Guan, Qing, Luo, Jianfei, Deng, Wenhong, Liu, Jiasheng, Yan, Ruicheng, Wang, Weixing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310191/ https://www.ncbi.nlm.nih.gov/pubmed/32571331 http://dx.doi.org/10.1186/s12885-020-07067-x |
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