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Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer

BACKGROUND: As a natural alkaloid product isolated from Sophora alopecuroides. L, Sophoridine reshapes gastric cancer immune microenvironment via inhibiting chemotaxis and M2 polarization of tumor-associated macrophages (TAMs). However, the exact effects and underlying mechanism of Sophoridine on ga...

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Detalles Bibliográficos
Autores principales: Peng, Zhiyang, Guan, Qing, Luo, Jianfei, Deng, Wenhong, Liu, Jiasheng, Yan, Ruicheng, Wang, Weixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310191/
https://www.ncbi.nlm.nih.gov/pubmed/32571331
http://dx.doi.org/10.1186/s12885-020-07067-x

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