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Six-minute walking distance in healthy Chinese people older than 60 years

BACKGROUND: The six-minute walking test (6MWT) is a tool that plays a key role in evaluating the functional exercise capacity, prognosis and evaluation of treatment response of patients with various cardiopulmonary diseases. However, standard reference equations are currently unavailable for the six...

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Autores principales: Zou, He, Zhang, Jia, Zou, Yingying, Chen, Xiaoshu, Wang, Yi, Chen, Hao, Ye, Fanhao, Yu, Haizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310198/
https://www.ncbi.nlm.nih.gov/pubmed/32571358
http://dx.doi.org/10.1186/s12890-020-01211-w
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author Zou, He
Zhang, Jia
Zou, Yingying
Chen, Xiaoshu
Wang, Yi
Chen, Hao
Ye, Fanhao
Yu, Haizhu
author_facet Zou, He
Zhang, Jia
Zou, Yingying
Chen, Xiaoshu
Wang, Yi
Chen, Hao
Ye, Fanhao
Yu, Haizhu
author_sort Zou, He
collection PubMed
description BACKGROUND: The six-minute walking test (6MWT) is a tool that plays a key role in evaluating the functional exercise capacity, prognosis and evaluation of treatment response of patients with various cardiopulmonary diseases. However, standard reference equations are currently unavailable for the six-minute walking distance (6MWD) for people aged 60–85 years in China. The purpose of this study was to 1) measure the 6MWD of healthy Chinese people aged 60–85 years, 2) establish reference equations for predicting the 6MWD, and 3) compare our reference equations with equations reported in previously published studies. METHOD: We obtained informed consent from each participant prior to the test, and the research design was approved by the Ethics Committee of Wenzhou People’s Hospital. The demographic and anthropometric data and the 6MWD of healthy Chinese subjects aged 60–85 years old were measured using a standardized protocol. Every subject completed two 6MWTs, and the longest 6MWD further analyzed. RESULTS: Two hundred sixty-six subjects (128 males and 138 females) completed the 6MWT, and the mean walking distance was 518 ± 72 m. Males achieved a longer walking distance than females (518 ± 72 m vs. 487 ± 70 m; p < 0.0001), and active subjects achieved a longer walking distance than nonactive subjects (512 ± 76 m vs. 485 ± 63 m; p < 0.0001). According to the univariate analysis, the 6MWD was significantly associated with age, height, body mass index (BMI), heart rate and blood pressure after exercise and changes in heart rate before and after exercise. The stepwise multivariate regression analysis identified age, height and BMI as independent predictors of the 6MWD. The reference equations for Caucasians and South Americans tended to overestimate the 6MWD of our subjects, while the equations for Asian and African populations tended to underestimate the 6MWD. CONCLUSIONS: This study is the first to describe the 6MWD of healthy Chinese people aged 60–85 years, and reference prediction equations were proposed. These findings will help to improve the evaluation of Chinese patients with diseases that affect exercise capacity.
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spelling pubmed-73101982020-06-23 Six-minute walking distance in healthy Chinese people older than 60 years Zou, He Zhang, Jia Zou, Yingying Chen, Xiaoshu Wang, Yi Chen, Hao Ye, Fanhao Yu, Haizhu BMC Pulm Med Research Article BACKGROUND: The six-minute walking test (6MWT) is a tool that plays a key role in evaluating the functional exercise capacity, prognosis and evaluation of treatment response of patients with various cardiopulmonary diseases. However, standard reference equations are currently unavailable for the six-minute walking distance (6MWD) for people aged 60–85 years in China. The purpose of this study was to 1) measure the 6MWD of healthy Chinese people aged 60–85 years, 2) establish reference equations for predicting the 6MWD, and 3) compare our reference equations with equations reported in previously published studies. METHOD: We obtained informed consent from each participant prior to the test, and the research design was approved by the Ethics Committee of Wenzhou People’s Hospital. The demographic and anthropometric data and the 6MWD of healthy Chinese subjects aged 60–85 years old were measured using a standardized protocol. Every subject completed two 6MWTs, and the longest 6MWD further analyzed. RESULTS: Two hundred sixty-six subjects (128 males and 138 females) completed the 6MWT, and the mean walking distance was 518 ± 72 m. Males achieved a longer walking distance than females (518 ± 72 m vs. 487 ± 70 m; p < 0.0001), and active subjects achieved a longer walking distance than nonactive subjects (512 ± 76 m vs. 485 ± 63 m; p < 0.0001). According to the univariate analysis, the 6MWD was significantly associated with age, height, body mass index (BMI), heart rate and blood pressure after exercise and changes in heart rate before and after exercise. The stepwise multivariate regression analysis identified age, height and BMI as independent predictors of the 6MWD. The reference equations for Caucasians and South Americans tended to overestimate the 6MWD of our subjects, while the equations for Asian and African populations tended to underestimate the 6MWD. CONCLUSIONS: This study is the first to describe the 6MWD of healthy Chinese people aged 60–85 years, and reference prediction equations were proposed. These findings will help to improve the evaluation of Chinese patients with diseases that affect exercise capacity. BioMed Central 2020-06-22 /pmc/articles/PMC7310198/ /pubmed/32571358 http://dx.doi.org/10.1186/s12890-020-01211-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Zou, He
Zhang, Jia
Zou, Yingying
Chen, Xiaoshu
Wang, Yi
Chen, Hao
Ye, Fanhao
Yu, Haizhu
Six-minute walking distance in healthy Chinese people older than 60 years
title Six-minute walking distance in healthy Chinese people older than 60 years
title_full Six-minute walking distance in healthy Chinese people older than 60 years
title_fullStr Six-minute walking distance in healthy Chinese people older than 60 years
title_full_unstemmed Six-minute walking distance in healthy Chinese people older than 60 years
title_short Six-minute walking distance in healthy Chinese people older than 60 years
title_sort six-minute walking distance in healthy chinese people older than 60 years
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310198/
https://www.ncbi.nlm.nih.gov/pubmed/32571358
http://dx.doi.org/10.1186/s12890-020-01211-w
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