DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification

OBJECTIVE: Vascular calcification is a pathology characterized by arterial mineralization, which is a common late-term complication of atherosclerosis that independently increases the risk of adverse cardiovascular events by fourfold. A major source of calcifying cells is transdifferentiating vascul...

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Detalles Bibliográficos
Autores principales: Ngai, David, Lino, Marsel, Rothenberg, Katheryn E., Simmons, Craig A., Fernandez-Gonzalez, Rodrigo, Bendeck, Michelle P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310304/
https://www.ncbi.nlm.nih.gov/pubmed/32493168
http://dx.doi.org/10.1161/ATVBAHA.120.314697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310304/
https://www.ncbi.nlm.nih.gov/pubmed/32493168
http://dx.doi.org/10.1161/ATVBAHA.120.314697

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