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DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification
OBJECTIVE: Vascular calcification is a pathology characterized by arterial mineralization, which is a common late-term complication of atherosclerosis that independently increases the risk of adverse cardiovascular events by fourfold. A major source of calcifying cells is transdifferentiating vascul...
Autores principales: | Ngai, David, Lino, Marsel, Rothenberg, Katheryn E., Simmons, Craig A., Fernandez-Gonzalez, Rodrigo, Bendeck, Michelle P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310304/ https://www.ncbi.nlm.nih.gov/pubmed/32493168 http://dx.doi.org/10.1161/ATVBAHA.120.314697 |
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