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A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy

The differential diagnosis of optic neuritis is broad and varied. We report the case of a 24-year-old Brazilian man who presented with five-week history of fever, malaise, myalgia, severe fatigue, tender right preauricular lymphadenopathy, and acute vision blurring associated with right optic disc s...

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Detalles Bibliográficos
Autores principales: Eyer-Silva, Walter de Araujo, Wutke, Letícia Stéfanie Curvello, Paiva, Alexandre de Carvalho Mendes, da Silva, Guilherme Almeida Rosa, Ferry, Fernando Raphael de Almeida, Signorini, Dario José Hart Pontes, de Oliveira, Jonathan Gonçalves, Lemos, Elba Regina Sampaio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310359/
https://www.ncbi.nlm.nih.gov/pubmed/32578704
http://dx.doi.org/10.1590/0037-8682-0516-2019
Descripción
Sumario:The differential diagnosis of optic neuritis is broad and varied. We report the case of a 24-year-old Brazilian man who presented with five-week history of fever, malaise, myalgia, severe fatigue, tender right preauricular lymphadenopathy, and acute vision blurring associated with right optic disc swelling and exudates in a macular star pattern. His illness developed soon after an infestation of fleas broke out among his cats. Diagnosis of ocular bartonellosis was confirmed by serological and molecular analyses targeting amplification of Bartonella spp. htrA gene. Signs and symptoms only improved after initiation of antimicrobial therapy.