A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy

The differential diagnosis of optic neuritis is broad and varied. We report the case of a 24-year-old Brazilian man who presented with five-week history of fever, malaise, myalgia, severe fatigue, tender right preauricular lymphadenopathy, and acute vision blurring associated with right optic disc s...

Descripción completa

Detalles Bibliográficos
Autores principales: Eyer-Silva, Walter de Araujo, Wutke, Letícia Stéfanie Curvello, Paiva, Alexandre de Carvalho Mendes, da Silva, Guilherme Almeida Rosa, Ferry, Fernando Raphael de Almeida, Signorini, Dario José Hart Pontes, de Oliveira, Jonathan Gonçalves, Lemos, Elba Regina Sampaio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310359/
https://www.ncbi.nlm.nih.gov/pubmed/32578704
http://dx.doi.org/10.1590/0037-8682-0516-2019
_version_ 1783549353644785664
author Eyer-Silva, Walter de Araujo
Wutke, Letícia Stéfanie Curvello
Paiva, Alexandre de Carvalho Mendes
da Silva, Guilherme Almeida Rosa
Ferry, Fernando Raphael de Almeida
Signorini, Dario José Hart Pontes
de Oliveira, Jonathan Gonçalves
Lemos, Elba Regina Sampaio
author_facet Eyer-Silva, Walter de Araujo
Wutke, Letícia Stéfanie Curvello
Paiva, Alexandre de Carvalho Mendes
da Silva, Guilherme Almeida Rosa
Ferry, Fernando Raphael de Almeida
Signorini, Dario José Hart Pontes
de Oliveira, Jonathan Gonçalves
Lemos, Elba Regina Sampaio
author_sort Eyer-Silva, Walter de Araujo
collection PubMed
description The differential diagnosis of optic neuritis is broad and varied. We report the case of a 24-year-old Brazilian man who presented with five-week history of fever, malaise, myalgia, severe fatigue, tender right preauricular lymphadenopathy, and acute vision blurring associated with right optic disc swelling and exudates in a macular star pattern. His illness developed soon after an infestation of fleas broke out among his cats. Diagnosis of ocular bartonellosis was confirmed by serological and molecular analyses targeting amplification of Bartonella spp. htrA gene. Signs and symptoms only improved after initiation of antimicrobial therapy.
format Online
Article
Text
id pubmed-7310359
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Sociedade Brasileira de Medicina Tropical - SBMT
record_format MEDLINE/PubMed
spelling pubmed-73103592020-06-24 A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy Eyer-Silva, Walter de Araujo Wutke, Letícia Stéfanie Curvello Paiva, Alexandre de Carvalho Mendes da Silva, Guilherme Almeida Rosa Ferry, Fernando Raphael de Almeida Signorini, Dario José Hart Pontes de Oliveira, Jonathan Gonçalves Lemos, Elba Regina Sampaio Rev Soc Bras Med Trop Case Report The differential diagnosis of optic neuritis is broad and varied. We report the case of a 24-year-old Brazilian man who presented with five-week history of fever, malaise, myalgia, severe fatigue, tender right preauricular lymphadenopathy, and acute vision blurring associated with right optic disc swelling and exudates in a macular star pattern. His illness developed soon after an infestation of fleas broke out among his cats. Diagnosis of ocular bartonellosis was confirmed by serological and molecular analyses targeting amplification of Bartonella spp. htrA gene. Signs and symptoms only improved after initiation of antimicrobial therapy. Sociedade Brasileira de Medicina Tropical - SBMT 2020-06-22 /pmc/articles/PMC7310359/ /pubmed/32578704 http://dx.doi.org/10.1590/0037-8682-0516-2019 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Case Report
Eyer-Silva, Walter de Araujo
Wutke, Letícia Stéfanie Curvello
Paiva, Alexandre de Carvalho Mendes
da Silva, Guilherme Almeida Rosa
Ferry, Fernando Raphael de Almeida
Signorini, Dario José Hart Pontes
de Oliveira, Jonathan Gonçalves
Lemos, Elba Regina Sampaio
A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy
title A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy
title_full A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy
title_fullStr A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy
title_full_unstemmed A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy
title_short A case of Bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy
title_sort case of bartonella neuroretinitis with macular star diagnosed by clinical, epidemiological, serological, and molecular data: resolution after initiation of antimicrobial therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310359/
https://www.ncbi.nlm.nih.gov/pubmed/32578704
http://dx.doi.org/10.1590/0037-8682-0516-2019
work_keys_str_mv AT eyersilvawalterdearaujo acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT wutkeleticiastefaniecurvello acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT paivaalexandredecarvalhomendes acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT dasilvaguilhermealmeidarosa acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT ferryfernandoraphaeldealmeida acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT signorinidariojosehartpontes acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT deoliveirajonathangoncalves acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT lemoselbareginasampaio acaseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT eyersilvawalterdearaujo caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT wutkeleticiastefaniecurvello caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT paivaalexandredecarvalhomendes caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT dasilvaguilhermealmeidarosa caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT ferryfernandoraphaeldealmeida caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT signorinidariojosehartpontes caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT deoliveirajonathangoncalves caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy
AT lemoselbareginasampaio caseofbartonellaneuroretinitiswithmacularstardiagnosedbyclinicalepidemiologicalserologicalandmoleculardataresolutionafterinitiationofantimicrobialtherapy

Ejemplares similares