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Mucocutaneous leishmaniasis in a cocaine user: diagnostic and therapeutic knowledge

Mucocutaneous leishmaniasis (MCL) is a chronic infection that can affect the skin and mucous membranes. We report a case of oral, nasopharyngeal, and penile lesions in a 35-year-old cocaine user. The patient presented with ulcerated lesions in 2014. Histopathologic analysis revealed amastigotes, and...

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Detalles Bibliográficos
Autores principales: Sbroglio, Lissiê Lunardi, Maiolini, Viviane Maria, Rabelo, Irene Machado Moraes Alvarenga, Giraldelli, Gabriela Almeida, Tuccori, Luciana Patrícia, Cunha, Rodrigo Guimarães
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310364/
https://www.ncbi.nlm.nih.gov/pubmed/32578710
http://dx.doi.org/10.1590/0037-8682-0040-2020
Descripción
Sumario:Mucocutaneous leishmaniasis (MCL) is a chronic infection that can affect the skin and mucous membranes. We report a case of oral, nasopharyngeal, and penile lesions in a 35-year-old cocaine user. The patient presented with ulcerated lesions in 2014. Histopathologic analysis revealed amastigotes, and serological test results were positive for leishmaniasis. Systemic therapy with meglumine antimoniate was administered; however, the patient failed to present for follow-up. In 2018, he returned with nasal collapse, and another histopathologic test confirmed MCL. This case illustrates the importance of careful differential diagnosis of skin and mucous ulcers to identify the particular pathology.