Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections

INTRODUCTION: The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital. METHODS: A retrospective cohort study was conducted in a Brazilian te...

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Autores principales: Sabino, Sebastiana Silva, de Lima, Caio Augusto, Machado, Luiz Gustavo, de Campos, Paola Amaral, Fontes, Astrídia Marília de Souza, Gontijo-Filho, Paulo Pinto, Ribas, Rosineide Marques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310365/
https://www.ncbi.nlm.nih.gov/pubmed/32578698
http://dx.doi.org/10.1590/0037-8682-0106-2019
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author Sabino, Sebastiana Silva
de Lima, Caio Augusto
Machado, Luiz Gustavo
de Campos, Paola Amaral
Fontes, Astrídia Marília de Souza
Gontijo-Filho, Paulo Pinto
Ribas, Rosineide Marques
author_facet Sabino, Sebastiana Silva
de Lima, Caio Augusto
Machado, Luiz Gustavo
de Campos, Paola Amaral
Fontes, Astrídia Marília de Souza
Gontijo-Filho, Paulo Pinto
Ribas, Rosineide Marques
author_sort Sabino, Sebastiana Silva
collection PubMed
description INTRODUCTION: The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital. METHODS: A retrospective cohort study was conducted in a Brazilian teaching hospital between 2012 and 2014. RESULTS: Overall, 81.2% of the infections were acquired in the ICU. The most common resistant pathogenic phenotypes in all-site and bloodstream infections were oxacillin-resistant coagulase-negative staphylococci and carbapenem-resistant Acinetobacter spp. (89.9% and 87.4%; 80.6% and 70.0%), respectively. CONCLUSIONS: There is an urgent need to focus on HCAIs in ICUs in Brazil.
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spelling pubmed-73103652020-06-24 Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections Sabino, Sebastiana Silva de Lima, Caio Augusto Machado, Luiz Gustavo de Campos, Paola Amaral Fontes, Astrídia Marília de Souza Gontijo-Filho, Paulo Pinto Ribas, Rosineide Marques Rev Soc Bras Med Trop Short Communication INTRODUCTION: The present study aimed to determine the incidence of health care-associated infections (HCAIs) and identify the main resistant microorganisms in intensive care unit (ICU) patients in a Brazilian university hospital. METHODS: A retrospective cohort study was conducted in a Brazilian teaching hospital between 2012 and 2014. RESULTS: Overall, 81.2% of the infections were acquired in the ICU. The most common resistant pathogenic phenotypes in all-site and bloodstream infections were oxacillin-resistant coagulase-negative staphylococci and carbapenem-resistant Acinetobacter spp. (89.9% and 87.4%; 80.6% and 70.0%), respectively. CONCLUSIONS: There is an urgent need to focus on HCAIs in ICUs in Brazil. Sociedade Brasileira de Medicina Tropical - SBMT 2020-06-22 /pmc/articles/PMC7310365/ /pubmed/32578698 http://dx.doi.org/10.1590/0037-8682-0106-2019 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
Sabino, Sebastiana Silva
de Lima, Caio Augusto
Machado, Luiz Gustavo
de Campos, Paola Amaral
Fontes, Astrídia Marília de Souza
Gontijo-Filho, Paulo Pinto
Ribas, Rosineide Marques
Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
title Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
title_full Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
title_fullStr Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
title_full_unstemmed Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
title_short Infections and antimicrobial resistance in an adult intensive care unit in a Brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
title_sort infections and antimicrobial resistance in an adult intensive care unit in a brazilian hospital and the influence of drug resistance on the thirty-day mortality among patients with bloodstream infections
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310365/
https://www.ncbi.nlm.nih.gov/pubmed/32578698
http://dx.doi.org/10.1590/0037-8682-0106-2019
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