Cargando…
Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether–lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania: a randomized controlled trial
BACKGROUND: Artemisinin-based combination therapy (ACT) resistant Plasmodium falciparum represents an increasing threat to Africa. Extended ACT regimens from standard 3 to 6 days may represent a means to prevent its development and potential spread in Africa. METHODS: Standard 3-day treatment with a...
Autores principales: | Mhamilawa, Lwidiko E., Ngasala, Billy, Morris, Ulrika, Kitabi, Eliford Ngaimisi, Barnes, Rory, Soe, Aung Paing, Mmbando, Bruno P., Björkman, Anders, Mårtensson, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310382/ https://www.ncbi.nlm.nih.gov/pubmed/32576258 http://dx.doi.org/10.1186/s12936-020-03287-5 |
Ejemplares similares
-
Electrocardiographic safety evaluation of extended artemether-lumefantrine treatment in patients with uncomplicated Plasmodium falciparum malaria in Bagamoyo District, Tanzania
por: Mhamilawa, Lwidiko E., et al.
Publicado: (2020) -
Prevalence of and Risk Factors Associated with Polymerase Chain Reaction-Determined Plasmodium falciparum Positivity on Day 3 after Initiation of Artemether–Lumefantrine Treatment for Uncomplicated Malaria in Bagamoyo District, Tanzania
por: Mwaiswelo, Richard, et al.
Publicado: (2019) -
Safety of a single low-dose of primaquine in addition to standard artemether-lumefantrine regimen for treatment of acute uncomplicated Plasmodium falciparum malaria in Tanzania
por: Mwaiswelo, Richard, et al.
Publicado: (2016) -
Temporal trends of molecular markers associated with artemether-lumefantrine tolerance/resistance in Bagamoyo district, Tanzania
por: Malmberg, Maja, et al.
Publicado: (2013) -
Adding a single low-dose of primaquine (0.25 mg/kg) to artemether-lumefantrine did not compromise treatment outcome of uncomplicated Plasmodium falciparum malaria in Tanzania: a randomized, single-blinded clinical trial
por: Mwaiswelo, Richard, et al.
Publicado: (2016)