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Enteral nutrition for severe malnutrition Crohn's disease patient: Case report

INTRODUCTION: Crohn's disease (CD) is a chronic systemic inflammatory disease with indefinite remission and relapse cycles, which can result in a high incidence rate of malnutrition. There has been increasing clinical interest in enteral nutrition (EN) as an adjunct treatment for CD. This repor...

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Autores principales: Li, Xuemei, You, Qian, Song, Yang, Shi, Lei, Hu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310884/
https://www.ncbi.nlm.nih.gov/pubmed/32569158
http://dx.doi.org/10.1097/MD.0000000000020112
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author Li, Xuemei
You, Qian
Song, Yang
Shi, Lei
Hu, Wen
author_facet Li, Xuemei
You, Qian
Song, Yang
Shi, Lei
Hu, Wen
author_sort Li, Xuemei
collection PubMed
description INTRODUCTION: Crohn's disease (CD) is a chronic systemic inflammatory disease with indefinite remission and relapse cycles, which can result in a high incidence rate of malnutrition. There has been increasing clinical interest in enteral nutrition (EN) as an adjunct treatment for CD. This report aims to present a case of a severely malnourished CD patient given EN support in combination with conventional infliximab (IFX) treatment. PATIENT CONCERNS: A 42-year-old CD patient with severe malnutrition. She once weighted 27.5 kg (BMI 11.4 kg/m(2)) with hyponatremia, which may cause sudden death at any time. DIAGNOSIS: In this study, the diagnosis of CD made by our gastroenterologist was based on integrating patient symptoms, radiologic findings, and biopsy results. The patient had no differential diagnosis. INTERVENTIONS: The patient received EN support and actively followed up for more than 2 years. The patient also received IFX treatment and four surgeries on an as-needed basis to manage her symptoms. OUTCOMES: The patient's inflammation and symptoms were finally improved by a combination of enteral nutrition and IFX, and her body weight increased to 44 kg. CONCLUSION: The jejunal feeding tube was the starting point of her weight gain and inflammation reduction, which allowed her adequate energy. EN may be a potential complementary therapeutic strategy to manage clinical symptoms of CD and improve severe malnutrition.
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spelling pubmed-73108842020-07-08 Enteral nutrition for severe malnutrition Crohn's disease patient: Case report Li, Xuemei You, Qian Song, Yang Shi, Lei Hu, Wen Medicine (Baltimore) 5500 INTRODUCTION: Crohn's disease (CD) is a chronic systemic inflammatory disease with indefinite remission and relapse cycles, which can result in a high incidence rate of malnutrition. There has been increasing clinical interest in enteral nutrition (EN) as an adjunct treatment for CD. This report aims to present a case of a severely malnourished CD patient given EN support in combination with conventional infliximab (IFX) treatment. PATIENT CONCERNS: A 42-year-old CD patient with severe malnutrition. She once weighted 27.5 kg (BMI 11.4 kg/m(2)) with hyponatremia, which may cause sudden death at any time. DIAGNOSIS: In this study, the diagnosis of CD made by our gastroenterologist was based on integrating patient symptoms, radiologic findings, and biopsy results. The patient had no differential diagnosis. INTERVENTIONS: The patient received EN support and actively followed up for more than 2 years. The patient also received IFX treatment and four surgeries on an as-needed basis to manage her symptoms. OUTCOMES: The patient's inflammation and symptoms were finally improved by a combination of enteral nutrition and IFX, and her body weight increased to 44 kg. CONCLUSION: The jejunal feeding tube was the starting point of her weight gain and inflammation reduction, which allowed her adequate energy. EN may be a potential complementary therapeutic strategy to manage clinical symptoms of CD and improve severe malnutrition. Wolters Kluwer Health 2020-06-19 /pmc/articles/PMC7310884/ /pubmed/32569158 http://dx.doi.org/10.1097/MD.0000000000020112 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 5500
Li, Xuemei
You, Qian
Song, Yang
Shi, Lei
Hu, Wen
Enteral nutrition for severe malnutrition Crohn's disease patient: Case report
title Enteral nutrition for severe malnutrition Crohn's disease patient: Case report
title_full Enteral nutrition for severe malnutrition Crohn's disease patient: Case report
title_fullStr Enteral nutrition for severe malnutrition Crohn's disease patient: Case report
title_full_unstemmed Enteral nutrition for severe malnutrition Crohn's disease patient: Case report
title_short Enteral nutrition for severe malnutrition Crohn's disease patient: Case report
title_sort enteral nutrition for severe malnutrition crohn's disease patient: case report
topic 5500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310884/
https://www.ncbi.nlm.nih.gov/pubmed/32569158
http://dx.doi.org/10.1097/MD.0000000000020112
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