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Intracystic papillary carcinoma of the breast in males: Three case reports
RATIONALE: Intracystic papillary breast carcinoma is extremely rare in males with a favorable prognosis. Clinical and mammographic manifestations of IPC are not specific, and no consensus has been reached on its management. PATIENT CONCERNS: Three cases of IPC of the breast in male patients who unde...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310891/ https://www.ncbi.nlm.nih.gov/pubmed/32569161 http://dx.doi.org/10.1097/MD.0000000000020278 |
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author | Luo, Hua Meng, Kexin He, Junling Hu, Zujian Yang, Ouou Lan, Tian Su, Kunlun Yang, Huifen Zhan, Chenni Xu, Haibin |
author_facet | Luo, Hua Meng, Kexin He, Junling Hu, Zujian Yang, Ouou Lan, Tian Su, Kunlun Yang, Huifen Zhan, Chenni Xu, Haibin |
author_sort | Luo, Hua |
collection | PubMed |
description | RATIONALE: Intracystic papillary breast carcinoma is extremely rare in males with a favorable prognosis. Clinical and mammographic manifestations of IPC are not specific, and no consensus has been reached on its management. PATIENT CONCERNS: Three cases of IPC of the breast in male patients who underwent surgery are presented. In each patient, clinical manifestations, radiological appearance, surgical procedures, pathological diagnosis, and prognosis were investigated. DIAGNOSIS: Ultrasonography showed a complex mass with cystic and nodular solid components in 2 patients and a solid hypoechoic mass in the other 1. Contrast-enhanced ultrasonography(CEUS) was performed for 1 patient demonstrated a solid component of the characteristic enhancement patterns. The final diagnosis of IPC was made after an excisional biopsy. INTERVENTIONS: A mastectomy with sentinel lymph node mapping was carried out in 2 patients, and it was negative for metastatic disease. The third patient received a mastectomy without an investigation of the axillary lymph node status. OUTCOMES: All the patients are disease-free during a median follow-up of 67 months (range, 13–120) months. LESSONS: It is difficult to diagnose IPC of the male breast before surgery, excisional biopsy is necessary. CEUS can be useful to diagnose IPC in male patients in the preoperative evaluation. Sentinel node biopsy may be considered in patients with IPC associated with DCIS or invasive carcinoma. |
format | Online Article Text |
id | pubmed-7310891 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-73108912020-07-08 Intracystic papillary carcinoma of the breast in males: Three case reports Luo, Hua Meng, Kexin He, Junling Hu, Zujian Yang, Ouou Lan, Tian Su, Kunlun Yang, Huifen Zhan, Chenni Xu, Haibin Medicine (Baltimore) 5750 RATIONALE: Intracystic papillary breast carcinoma is extremely rare in males with a favorable prognosis. Clinical and mammographic manifestations of IPC are not specific, and no consensus has been reached on its management. PATIENT CONCERNS: Three cases of IPC of the breast in male patients who underwent surgery are presented. In each patient, clinical manifestations, radiological appearance, surgical procedures, pathological diagnosis, and prognosis were investigated. DIAGNOSIS: Ultrasonography showed a complex mass with cystic and nodular solid components in 2 patients and a solid hypoechoic mass in the other 1. Contrast-enhanced ultrasonography(CEUS) was performed for 1 patient demonstrated a solid component of the characteristic enhancement patterns. The final diagnosis of IPC was made after an excisional biopsy. INTERVENTIONS: A mastectomy with sentinel lymph node mapping was carried out in 2 patients, and it was negative for metastatic disease. The third patient received a mastectomy without an investigation of the axillary lymph node status. OUTCOMES: All the patients are disease-free during a median follow-up of 67 months (range, 13–120) months. LESSONS: It is difficult to diagnose IPC of the male breast before surgery, excisional biopsy is necessary. CEUS can be useful to diagnose IPC in male patients in the preoperative evaluation. Sentinel node biopsy may be considered in patients with IPC associated with DCIS or invasive carcinoma. Wolters Kluwer Health 2020-06-19 /pmc/articles/PMC7310891/ /pubmed/32569161 http://dx.doi.org/10.1097/MD.0000000000020278 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5750 Luo, Hua Meng, Kexin He, Junling Hu, Zujian Yang, Ouou Lan, Tian Su, Kunlun Yang, Huifen Zhan, Chenni Xu, Haibin Intracystic papillary carcinoma of the breast in males: Three case reports |
title | Intracystic papillary carcinoma of the breast in males: Three case reports |
title_full | Intracystic papillary carcinoma of the breast in males: Three case reports |
title_fullStr | Intracystic papillary carcinoma of the breast in males: Three case reports |
title_full_unstemmed | Intracystic papillary carcinoma of the breast in males: Three case reports |
title_short | Intracystic papillary carcinoma of the breast in males: Three case reports |
title_sort | intracystic papillary carcinoma of the breast in males: three case reports |
topic | 5750 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310891/ https://www.ncbi.nlm.nih.gov/pubmed/32569161 http://dx.doi.org/10.1097/MD.0000000000020278 |
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