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Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis

INTRODUCTION: Opioid use disorder (OUD) is a worldwide health problem. Clinical trials indicated that acupuncture combined with medication is effective in OUD, however, there are different conclusions presented by previous trials. This study is designed to evaluate the efficacy and safety of acupunc...

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Autores principales: Chen, Zhihan, Wang, Rui, Zhang, Min, Wang, Yitong, Ren, Yulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310998/
https://www.ncbi.nlm.nih.gov/pubmed/32565455
http://dx.doi.org/10.1136/bmjopen-2019-034554
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author Chen, Zhihan
Wang, Rui
Zhang, Min
Wang, Yitong
Ren, Yulan
author_facet Chen, Zhihan
Wang, Rui
Zhang, Min
Wang, Yitong
Ren, Yulan
author_sort Chen, Zhihan
collection PubMed
description INTRODUCTION: Opioid use disorder (OUD) is a worldwide health problem. Clinical trials indicated that acupuncture combined with medication is effective in OUD, however, there are different conclusions presented by previous trials. This study is designed to evaluate the efficacy and safety of acupuncture combined with medication in OUD. METHODS AND ANALYSIS: PubMed, CENTRAL, Embase, Web of Science, CINAHL, PsycINFO, ProQuest Dissertation and Theses, AMED, OpenGrey, Clinicaltrials.gov and who.int/trialsearch will be searched in September 2019 without a language restriction. Randomised controlled trials (RCTs) and quasi-RCTs which included participants with OUD receiving acupuncture therapy combined with medication versus control group will be included in this study. Two reviewers will independently screen studies, extract data, assess risk of bias by the Cochrane risk of bias assessment tool and assess quality of evidence by Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. Any disagreements will be arbitrated by the third reviewer. Data synthesis and analysis will be conducted by using RevMan V.5.3. Subgroup analyses, sensitivity analysis, meta-regression and reporting bias assessment will be conducted if necessary and appropriate. ETHICS AND DISSEMINATION: On account of the nature of this systematic review and meta-analysis, ethical approval is not required. The results will be published in a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42019123436.
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spelling pubmed-73109982020-06-26 Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis Chen, Zhihan Wang, Rui Zhang, Min Wang, Yitong Ren, Yulan BMJ Open Complementary Medicine INTRODUCTION: Opioid use disorder (OUD) is a worldwide health problem. Clinical trials indicated that acupuncture combined with medication is effective in OUD, however, there are different conclusions presented by previous trials. This study is designed to evaluate the efficacy and safety of acupuncture combined with medication in OUD. METHODS AND ANALYSIS: PubMed, CENTRAL, Embase, Web of Science, CINAHL, PsycINFO, ProQuest Dissertation and Theses, AMED, OpenGrey, Clinicaltrials.gov and who.int/trialsearch will be searched in September 2019 without a language restriction. Randomised controlled trials (RCTs) and quasi-RCTs which included participants with OUD receiving acupuncture therapy combined with medication versus control group will be included in this study. Two reviewers will independently screen studies, extract data, assess risk of bias by the Cochrane risk of bias assessment tool and assess quality of evidence by Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. Any disagreements will be arbitrated by the third reviewer. Data synthesis and analysis will be conducted by using RevMan V.5.3. Subgroup analyses, sensitivity analysis, meta-regression and reporting bias assessment will be conducted if necessary and appropriate. ETHICS AND DISSEMINATION: On account of the nature of this systematic review and meta-analysis, ethical approval is not required. The results will be published in a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42019123436. BMJ Publishing Group 2020-06-21 /pmc/articles/PMC7310998/ /pubmed/32565455 http://dx.doi.org/10.1136/bmjopen-2019-034554 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Complementary Medicine
Chen, Zhihan
Wang, Rui
Zhang, Min
Wang, Yitong
Ren, Yulan
Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis
title Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis
title_full Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis
title_fullStr Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis
title_full_unstemmed Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis
title_short Acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis
title_sort acupuncture combined with medication for opioid use disorder in adults: a protocol for systematic review and meta-analysis
topic Complementary Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310998/
https://www.ncbi.nlm.nih.gov/pubmed/32565455
http://dx.doi.org/10.1136/bmjopen-2019-034554
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