Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes

[Image: see text] An efficient palladium-catalyzed oxidative C–C bond forming cascade reaction of allenes involving a coupling between an enallene and an allenyne followed by a carbocyclization of the generated Pd-intermediate was developed. This cascade reaction afforded functionalized cross-conjug...

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Autores principales: Naidu, Veluru Ramesh, Bäckvall, Jan-E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311062/
https://www.ncbi.nlm.nih.gov/pubmed/32207975
http://dx.doi.org/10.1021/acs.joc.0c00186
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author Naidu, Veluru Ramesh
Bäckvall, Jan-E.
author_facet Naidu, Veluru Ramesh
Bäckvall, Jan-E.
author_sort Naidu, Veluru Ramesh
collection PubMed
description [Image: see text] An efficient palladium-catalyzed oxidative C–C bond forming cascade reaction of allenes involving a coupling between an enallene and an allenyne followed by a carbocyclization of the generated Pd-intermediate was developed. This cascade reaction afforded functionalized cross-conjugated polyenes. The enallene is initially activated by palladium and reacts with the allenyne to give the cross-conjugated polyenes.
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spelling pubmed-73110622020-06-24 Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes Naidu, Veluru Ramesh Bäckvall, Jan-E. J Org Chem [Image: see text] An efficient palladium-catalyzed oxidative C–C bond forming cascade reaction of allenes involving a coupling between an enallene and an allenyne followed by a carbocyclization of the generated Pd-intermediate was developed. This cascade reaction afforded functionalized cross-conjugated polyenes. The enallene is initially activated by palladium and reacts with the allenyne to give the cross-conjugated polyenes. American Chemical Society 2020-03-24 2020-04-17 /pmc/articles/PMC7311062/ /pubmed/32207975 http://dx.doi.org/10.1021/acs.joc.0c00186 Text en Copyright © 2020 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
spellingShingle Naidu, Veluru Ramesh
Bäckvall, Jan-E.
Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes
title Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes
title_full Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes
title_fullStr Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes
title_full_unstemmed Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes
title_short Synthesis of Cross-Conjugated Polyenes via Palladium-Catalyzed Oxidative C–C Bond Forming Cascade Reactions of Allenes
title_sort synthesis of cross-conjugated polyenes via palladium-catalyzed oxidative c–c bond forming cascade reactions of allenes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311062/
https://www.ncbi.nlm.nih.gov/pubmed/32207975
http://dx.doi.org/10.1021/acs.joc.0c00186
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