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Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

Generation of autologous human motor neurons holds great promise for cell replacement therapy to treat spinal cord injury (SCI). Direct conversion allows generation of target cells from somatic cells, however, current protocols are not practicable for therapeutic purposes since converted cells are p...

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Detalles Bibliográficos
Autores principales: Lee, Hyunah, Lee, Hye Yeong, Lee, Byeong Eun, Gerovska, Daniela, Park, Soo Yong, Zaehres, Holm, Araúzo-Bravo, Marcos J, Kim, Jae-Ick, Ha, Yoon, Schöler, Hans R, Kim, Jeong Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311175/
https://www.ncbi.nlm.nih.gov/pubmed/32571478
http://dx.doi.org/10.7554/eLife.52069