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Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction

The lysis of red blood cells was shown to occur in human ruptured atherosclerotic lesions and intraventricular hemorrhage (IVH) of the brain. Liberated cell-free hemoglobin was found to undergo oxidation in both pathologies. We hypothesize that hemoglobin-derived peptides are generated during hemogl...

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Detalles Bibliográficos
Autores principales:	Posta, Niké, Csősz, Éva, Oros, Melinda, Pethő, Dávid, Potor, László, Kalló, Gergő, Hendrik, Zoltán, Sikura, Katalin Éva, Méhes, Gábor, Tóth, Csaba, Posta, József, Balla, György, Balla, József
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311325/ https://www.ncbi.nlm.nih.gov/pubmed/32054994 http://dx.doi.org/10.1038/s41374-020-0403-x

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