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Paramagnetic NMR in drug discovery

The presence of an unpaired electron in paramagnetic molecules generates significant effects in NMR spectra, which can be exploited to provide restraints complementary to those used in standard structure-calculation protocols. NMR already occupies a central position in drug discovery for its use in...

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Detalles Bibliográficos
Autores principales:	Softley, Charlotte A., Bostock, Mark J., Popowicz, Grzegorz M., Sattler, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2020
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311382/ https://www.ncbi.nlm.nih.gov/pubmed/32524233 http://dx.doi.org/10.1007/s10858-020-00322-0

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