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Rad9/53BP1 promotes DNA repair via crossover recombination by limiting the Sgs1 and Mph1 helicases

The DNA damage checkpoint (DDC) is often robustly activated during the homologous recombination (HR) repair of DNA double strand breaks (DSBs). DDC activation controls several HR repair factors by phosphorylation, preventing premature segregation of entangled chromosomes formed during HR repair. The...

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Detalles Bibliográficos
Autores principales:	Ferrari, Matteo, Rawal, Chetan C., Lodovichi, Samuele, Vietri, Maria Y., Pellicioli, Achille
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311424/ https://www.ncbi.nlm.nih.gov/pubmed/32576832 http://dx.doi.org/10.1038/s41467-020-16997-w

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