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TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus (DENV) infection, but the mechanisms underlying the exacerbated inflammation during DENV pathogenesis are unclear. Here, we demonstrate that TLR2, together with its co-receptors CD14 and TLR6, is an innate sensor...

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Detalles Bibliográficos
Autores principales:	Aguilar-Briseño, José A., Upasani, Vinit, Ellen, Bram M. ter, Moser, Jill, Pauzuolis, Mindaugas, Ruiz-Silva, Mariana, Heng, Sothy, Laurent, Denis, Choeung, Rithy, Dussart, Philippe, Cantaert, Tineke, Smit, Jolanda M., Rodenhuis-Zybert, Izabela A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311456/ https://www.ncbi.nlm.nih.gov/pubmed/32576819 http://dx.doi.org/10.1038/s41467-020-16849-7

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