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SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites

Human single-stranded DNA-binding protein 1 (hSSB1) is required for the efficient recruitment of the MRN complex to DNA double-strand breaks and is essential for the maintenance of genome integrity. However, the mechanism by which hSSB1 recruits NBS1 remains elusive. Here, we determined that hSSB1 u...

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Detalles Bibliográficos
Autores principales:	Zhou, Liwen, Zheng, Lisi, Hu, Kaishun, Wang, Xin, Zhang, Ruhua, Zou, Yezi, Zhong, Li, Wang, Shang, Wu, Yuanzhong, Kang, Tiebang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311467/ https://www.ncbi.nlm.nih.gov/pubmed/32576812 http://dx.doi.org/10.1038/s41392-020-0172-4

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