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Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents

Potentially inappropriate medications (PIMs) can contribute to morbidity through exacerbations or progression of existing conditions among older people. In order to characterize the prevalence of PIMs according to the Beers Criteria in older Australians, three hundred and eleven participants were re...

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Autores principales: Bony, Hosam, Lloyd, Renae A., Hotham, Elizabeth D., Corre, Lauren J., Corlis, Megan E., Loffler, Helen A., Scarlett, Gregory K., Tsimbinos, Jacquie M., Todd, Ian P., Suppiah, Vijayaprakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311470/
https://www.ncbi.nlm.nih.gov/pubmed/32576947
http://dx.doi.org/10.1038/s41598-020-66991-x
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author Bony, Hosam
Lloyd, Renae A.
Hotham, Elizabeth D.
Corre, Lauren J.
Corlis, Megan E.
Loffler, Helen A.
Scarlett, Gregory K.
Tsimbinos, Jacquie M.
Todd, Ian P.
Suppiah, Vijayaprakash
author_facet Bony, Hosam
Lloyd, Renae A.
Hotham, Elizabeth D.
Corre, Lauren J.
Corlis, Megan E.
Loffler, Helen A.
Scarlett, Gregory K.
Tsimbinos, Jacquie M.
Todd, Ian P.
Suppiah, Vijayaprakash
author_sort Bony, Hosam
collection PubMed
description Potentially inappropriate medications (PIMs) can contribute to morbidity through exacerbations or progression of existing conditions among older people. In order to characterize the prevalence of PIMs according to the Beers Criteria in older Australians, three hundred and eleven participants were recruited from three residential aged care facilities (RACFs) and two hundred and twenty participants from three community pharmacies in South Australia for a retrospective audit of medication administration charts and community pharmacy dispensing histories. Although a similar number of participants were prescribed at least one PIM (P = 0.09), the average number of PIMs was significantly greater in the RACF cohort (1.96 vs 1.26, P < 0.05). Additionally, PIMs prescribed as pro re nata (PRN) in the RACF cohort had a significantly low administration rate compared to prescription rate (19.7% vs 40.7%). The mean number of PIMs within each cohort was statistically significant (RACF = 1.93 vs CDOA = 1.26, P < 0.05). RACF residents were at a slightly greater risk of being prescribed more than one PIM compared to those within the community. Routine medication reviews by pharmacists embedded in RACFs and within the community could be utilised to detect PIMs before such harm occurs.
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spelling pubmed-73114702020-06-25 Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents Bony, Hosam Lloyd, Renae A. Hotham, Elizabeth D. Corre, Lauren J. Corlis, Megan E. Loffler, Helen A. Scarlett, Gregory K. Tsimbinos, Jacquie M. Todd, Ian P. Suppiah, Vijayaprakash Sci Rep Article Potentially inappropriate medications (PIMs) can contribute to morbidity through exacerbations or progression of existing conditions among older people. In order to characterize the prevalence of PIMs according to the Beers Criteria in older Australians, three hundred and eleven participants were recruited from three residential aged care facilities (RACFs) and two hundred and twenty participants from three community pharmacies in South Australia for a retrospective audit of medication administration charts and community pharmacy dispensing histories. Although a similar number of participants were prescribed at least one PIM (P = 0.09), the average number of PIMs was significantly greater in the RACF cohort (1.96 vs 1.26, P < 0.05). Additionally, PIMs prescribed as pro re nata (PRN) in the RACF cohort had a significantly low administration rate compared to prescription rate (19.7% vs 40.7%). The mean number of PIMs within each cohort was statistically significant (RACF = 1.93 vs CDOA = 1.26, P < 0.05). RACF residents were at a slightly greater risk of being prescribed more than one PIM compared to those within the community. Routine medication reviews by pharmacists embedded in RACFs and within the community could be utilised to detect PIMs before such harm occurs. Nature Publishing Group UK 2020-06-23 /pmc/articles/PMC7311470/ /pubmed/32576947 http://dx.doi.org/10.1038/s41598-020-66991-x Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Bony, Hosam
Lloyd, Renae A.
Hotham, Elizabeth D.
Corre, Lauren J.
Corlis, Megan E.
Loffler, Helen A.
Scarlett, Gregory K.
Tsimbinos, Jacquie M.
Todd, Ian P.
Suppiah, Vijayaprakash
Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents
title Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents
title_full Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents
title_fullStr Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents
title_full_unstemmed Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents
title_short Differences in the prescribing of potentially inappropriate medicines in older Australians: comparison of community dwelling and residential aged care residents
title_sort differences in the prescribing of potentially inappropriate medicines in older australians: comparison of community dwelling and residential aged care residents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311470/
https://www.ncbi.nlm.nih.gov/pubmed/32576947
http://dx.doi.org/10.1038/s41598-020-66991-x
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