β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593

Actinomycetes bacteria produce diverse bioactive molecules that are useful as drug seeds. To improve their yield, researchers often optimize the fermentation medium. However, exactly how the extracellular chemicals present in the medium activate secondary metabolite gene clusters remains unresolved....

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Detalles Bibliográficos
Autores principales: Panthee, Suresh, Kito, Naoko, Hayashi, Teruo, Shimizu, Takeshi, Ishikawa, Jun, Hamamoto, Hiroshi, Osada, Hiroyuki, Takahashi, Shunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311520/
https://www.ncbi.nlm.nih.gov/pubmed/32576869
http://dx.doi.org/10.1038/s41598-020-66974-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311520/
https://www.ncbi.nlm.nih.gov/pubmed/32576869
http://dx.doi.org/10.1038/s41598-020-66974-y

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