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β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593
Actinomycetes bacteria produce diverse bioactive molecules that are useful as drug seeds. To improve their yield, researchers often optimize the fermentation medium. However, exactly how the extracellular chemicals present in the medium activate secondary metabolite gene clusters remains unresolved....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311520/ https://www.ncbi.nlm.nih.gov/pubmed/32576869 http://dx.doi.org/10.1038/s41598-020-66974-y |