Genome-wide DNA methylation analysis of KRAS mutant cell lines

Oncogenic RAS mutations are associated with DNA methylation changes that alter gene expression to drive cancer. Recent studies suggest that DNA methylation changes may be stochastic in nature, while other groups propose distinct signaling pathways responsible for aberrant methylation. Better underst...

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Detalles Bibliográficos
Autores principales: Tew, Ben Yi, Durand, Joel K., Bryant, Kirsten L., Hayes, Tikvah K., Peng, Sen, Tran, Nhan L., Gooden, Gerald C., Buckley, David N., Der, Channing J., Baldwin, Albert S., Salhia, Bodour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311523/
https://www.ncbi.nlm.nih.gov/pubmed/32576853
http://dx.doi.org/10.1038/s41598-020-66797-x

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