Asymmetry between Activators and Deactivators in Functional Protein Networks

Are “turn-on” and “turn-off” functions in protein-protein interaction networks exact opposites of each other? To answer this question, we implement a minimal model for the evolution of functional protein-interaction networks using a sequence-based mutational algorithm, and apply the model to study n...

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Detalles Bibliográficos
Autores principales: Tareen, Ammar, Wingreen, Ned S., Mukhopadhyay, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311538/
https://www.ncbi.nlm.nih.gov/pubmed/32576941
http://dx.doi.org/10.1038/s41598-020-66699-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311538/
https://www.ncbi.nlm.nih.gov/pubmed/32576941
http://dx.doi.org/10.1038/s41598-020-66699-y

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