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Asymmetry between Activators and Deactivators in Functional Protein Networks
Are “turn-on” and “turn-off” functions in protein-protein interaction networks exact opposites of each other? To answer this question, we implement a minimal model for the evolution of functional protein-interaction networks using a sequence-based mutational algorithm, and apply the model to study n...
Autores principales: | Tareen, Ammar, Wingreen, Ned S., Mukhopadhyay, Ranjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311538/ https://www.ncbi.nlm.nih.gov/pubmed/32576941 http://dx.doi.org/10.1038/s41598-020-66699-y |
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