Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion

Central nervous system ischemic injury features neuronal dysfunction, inflammation and breakdown of vascular integrity. Here we show that activation of endothelial caspase-9 after hypoxia-ischemia is a critical event in subsequent dysfunction of the blood-retina barrier, using a panel of interrelate...

Descripción completa

Detalles Bibliográficos
Autores principales: Avrutsky, Maria I., Ortiz, Crystal Colón, Johnson, Kendra V., Potenski, Anna M., Chen, Claire W., Lawson, Jacqueline M., White, Alexandra J., Yuen, Stephanie K., Morales, Fatima N., Canepa, Elisa, Snipas, Scott, Salvesen, Guy S., Jean, Ying Y., Troy, Carol M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311551/
https://www.ncbi.nlm.nih.gov/pubmed/32576823
http://dx.doi.org/10.1038/s41467-020-16902-5

Ejemplares similares

Ejemplares similares