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Co-treatments to Boost IDO Activity and Inhibit Production of Downstream Catabolites Induce Durable Suppression of Experimental Autoimmune Encephalomyelitis

Reinforcing defective tolerogenic processes slows progression of autoimmune (AI) diseases and has potential to promote drug-free disease remission. Previously, we reported that DNA nanoparticles (DNPs) and cyclic dinucleotides (CDNs) slow progression of experimental autoimmune encephalomyelitis (EAE...

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Detalles Bibliográficos
Autores principales:	Lemos, Henrique, Mohamed, Eslam, Ou, Rong, McCardle, Caroline, Zheng, Xiaozhong, McGuire, Kris, Homer, Natalie Z. M., Mole, Damian J., Huang, Lei, Mellor, Andrew L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311583/ https://www.ncbi.nlm.nih.gov/pubmed/32625215 http://dx.doi.org/10.3389/fimmu.2020.01256

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