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The Molecular-Container Calabadion-2 Prevents Methamphetamine-Induced Reinstatement in Rats: A Potential Approach to Relapse Prevention?

BACKGROUND: Reexposure to methamphetamine with a single “priming dose” can trigger intense cravings and precipitate relapse in methamphetamine-dependent individuals. The acyclic cucurbit[n]uril “molecular container” calabadion-2 shows a high affinity to bind and sequester methamphetamine in vitro an...

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Detalles Bibliográficos
Autores principales: Leonard, Michael Z, Rostin, Paul, Hill, Kevin P, Grabitz, Stephanie D, Eikermann, Matthias, Miczek, Klaus A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311644/
https://www.ncbi.nlm.nih.gov/pubmed/32531049
http://dx.doi.org/10.1093/ijnp/pyz070

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