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The C-Terminus Tail Regulates ERK3 Kinase Activity and Its Ability in Promoting Cancer Cell Migration and Invasion

Extracellular signal-regulated kinase 3 (ERK3) is an atypical member of the mitogen-activated protein kinase (MAPK) family. It harbors a kinase domain in the N-terminus and a long C-terminus extension. The C-terminus extension comprises a conserved in ERK3 and ERK4 (C34) region and a unique C-termin...

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Detalles Bibliográficos
Autores principales: Elkhadragy, Lobna, Alsaran, Hadel, Long, Weiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312006/
https://www.ncbi.nlm.nih.gov/pubmed/32516969
http://dx.doi.org/10.3390/ijms21114044