Cargando…

Ablation of the miRNA Cluster 24 Has Profound Effects on Extracellular Matrix Protein Abundance in Cartilage

MicroRNAs (miRNAs) regulate cartilage differentiation and contribute to the onset and progression of joint degeneration. These small RNA molecules may affect extracellular matrix organization (ECM) in cartilage, but for only a few miRNAs has this role been defined in vivo. Previously, we showed that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Georgieva, Veronika S., Etich, Julia, Bluhm, Björn, Zhu, Mengjie, Frie, Christian, Wilson, Richard, Zaucke, Frank, Bateman, John, Brachvogel, Bent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312048/ https://www.ncbi.nlm.nih.gov/pubmed/32526967 http://dx.doi.org/10.3390/ijms21114112

Ejemplares similares

Ablation of the miRNA cluster 24 in cartilage and osteoblasts impairs bone remodeling
por: Georgieva, Veronika S., et al.
Publicado: (2022)

Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases
por: Holzer, Tatjana, et al.
Publicado: (2019)

Gene Expression Profiling of the Extracellular Matrix Signature in Macrophages of Different Activation Status: Relevance for Skin Wound Healing
por: Etich, Julia, et al.
Publicado: (2019)

Global comparative transcriptome analysis of cartilage formation in vivo
por: Cameron, Trevor L, et al.
Publicado: (2009)

PECAM1(+)/Sca1(+)/CD38(+) Vascular Cells Transform into Myofibroblast-Like Cells in Skin Wound Repair
por: Etich, Julia, et al.
Publicado: (2013)

Thanks to all those who reviewed for Journal of Negative Results in Biomedicine in 2014
por: Olsen, Bjorn R, et al.
Publicado: (2015)

Human preterm colostrum stimulates outgrowth in neurogenic tissue
por: Kaps, Julian, et al.
Publicado: (2023)

Lactobacillus casei Abundance Is Associated with Profound Shifts in the Infant Gut Microbiome
por: Cox, Michael J., et al.
Publicado: (2010)

Editorial: Bone and Cartilage Regeneration With Extracellular Vesicles
por: Tasso, Roberta, et al.
Publicado: (2021)

Circadian Phase Has Profound Effects on Differential Expression Analysis
por: Hsu, Polly Yingshan, et al.
Publicado: (2012)

Canopy position has a profound effect on soybean seed composition
por: Huber, Steven C., et al.
Publicado: (2016)

Mosquito saliva alone has profound effects on the human immune system
por: Vogt, Megan B., et al.
Publicado: (2018)

Melatonin has profound effects on mitochondrial dynamics in myocardial ischaemia/reperfusion
por: Dube, K., et al.
Publicado: (2019)

Osteogenesis imperfecta—pathophysiology and therapeutic options
por: Etich, Julia, et al.
Publicado: (2020)

Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage
por: Bubb, Kristina, et al.
Publicado: (2021)

Reduced cellular binding affinity has profoundly different impacts on the spread of distinct poxviruses
por: Flores, Erica B., et al.
Publicado: (2020)

Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice
por: Brylka, Laura J., et al.
Publicado: (2017)

Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1
por: Nossin, Yannick, et al.
Publicado: (2020)

Physiologically relevant miRNAs in mammalian oocytes are rare and highly abundant
por: Kataruka, Shubhangini, et al.
Publicado: (2021)

Cartilage Oligomeric Matrix Protein–Derived Peptides Secreted by Cartilage Do Not Induce Responses Commonly Observed during Osteoarthritis
por: Andrés Sastre, Enrique, et al.
Publicado: (2020)

COMP and TSP-4: Functional Roles in Articular Cartilage and Relevance in Osteoarthritis
por: Maly, Kathrin, et al.
Publicado: (2021)

The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity
por: Zhou, Liang, et al.
Publicado: (2015)

The Role of miRNAs in Cartilage Homeostasis
por: Li, Yong Ping, et al.
Publicado: (2015)

The Expression of Thrombospondin-4 Correlates with Disease Severity in Osteoarthritic Knee Cartilage
por: Maly, Kathrin, et al.
Publicado: (2019)

Ablation of collagen XII disturbs joint extracellular matrix organization and causes patellar subluxation
por: Zhu, Mengjie, et al.
Publicado: (2023)

Choice of Nanovaccine Delivery Mode Has Profound Impacts on the Intralymph Node Spatiotemporal Distribution and Immunotherapy Efficacy
por: Wang, Jianghua, et al.
Publicado: (2020)

Relationship between different serum cartilage biomarkers in the acute response to running and jumping in healthy male individuals
por: Dreiner, Maren, et al.
Publicado: (2022)

MiRNA expression in the cartilage of patients with osteoarthritis
por: Kopańska, Marta, et al.
Publicado: (2017)

Case report: Managing profound circulatory collapse post-atrial fibrillation ablation: a methodical approach
por: Lim, Ven Gee, et al.
Publicado: (2020)

Profound or Phlegmonoid Erysipelas
por: Niemeier, George
Publicado: (1858)

Maternal inflammation has a profound effect on cortical interneuron development in a stage and subtype-specific manner
por: Vasistha, Navneet A., et al.
Publicado: (2019)

Author Correction: Relationship between different serum cartilage biomarkers in the acute response to running and jumping in healthy male individuals
por: Dreiner, Maren, et al.
Publicado: (2022)

Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition
por: Stoffel, Wilhelm, et al.
Publicado: (2016)

The Hexosamine Biosynthetic Pathway as a Therapeutic Target after Cartilage Trauma: Modification of Chondrocyte Survival and Metabolism by Glucosamine Derivatives and PUGNAc in an Ex Vivo Model
por: Riegger, Jana, et al.
Publicado: (2021)

β1 Integrins Mediate Attachment of Mesenchymal Stem Cells to Cartilage Lesions
por: Zwolanek, Daniela, et al.
Publicado: (2015)

Erratum to: MiRNA expression in the cartilage of patients with osteoarthritis
por: Kopańska, Marta, et al.
Publicado: (2017)

Inhibition of CCL2 Signaling in Combination with Docetaxel Treatment Has Profound Inhibitory Effects on Prostate Cancer Growth in Bone
por: Kirk, Peter S., et al.
Publicado: (2013)

Phosphoglycolate has profound metabolic effects but most likely no role in a metabolic DNA response in cancer cell lines
por: Gerin, Isabelle, et al.
Publicado: (2019)

An altered heparan sulfate structure in the articular cartilage protects against osteoarthritis
por: Severmann, A.-C., et al.
Publicado: (2020)

Effects of root and leaf litter identity and diversity on oribatid mite abundance, species richness and community composition
por: Bluhm, Christian, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2404vb145qao6qnh7nqkecir0f