Cargando…
Overview of Mitochondrial E3 Ubiquitin Ligase MITOL/MARCH5 from Molecular Mechanisms to Diseases
The molecular pathology of diseases seen from the mitochondrial axis has become more complex with the progression of research. A variety of factors, including the failure of mitochondrial dynamics and quality control, have made it extremely difficult to narrow down drug discovery targets. We have id...
Autores principales: | Shiiba, Isshin, Takeda, Keisuke, Nagashima, Shun, Yanagi, Shigeru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312067/ https://www.ncbi.nlm.nih.gov/pubmed/32471110 http://dx.doi.org/10.3390/ijms21113781 |
Ejemplares similares
-
MITOL promotes cell survival by degrading Parkin during mitophagy
por: Shiiba, Isshin, et al.
Publicado: (2021) -
MITOL prevents ER stress‐induced apoptosis by IRE1α ubiquitylation at ER–mitochondria contact sites
por: Takeda, Keisuke, et al.
Publicado: (2019) -
Mitochondrial ubiquitin ligase alleviates Alzheimer’s disease pathology via blocking the toxic amyloid-β oligomer generation
por: Takeda, Keisuke, et al.
Publicado: (2021) -
Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation
por: Tokuyama, Takeshi, et al.
Publicado: (2022) -
MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress
por: Nagashima, Shun, et al.
Publicado: (2019)