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AMPK Profiling in Rodent and Human Pancreatic Beta-Cells under Nutrient-Rich Metabolic Stress
Chronic exposure of pancreatic β-cells to elevated nutrient levels impairs their function and potentially induces apoptosis. Like in other cell types, AMPK is activated in β-cells under conditions of nutrient deprivation, while little is known on AMPK responses to metabolic stresses. Here, we first...
Autores principales: | Brun, Thierry, Jiménez-Sánchez, Cecilia, Madsen, Jesper Grud Skat, Hadadi, Noushin, Duhamel, Dominique, Bartley, Clarissa, Oberhauser, Lucie, Trajkovski, Mirko, Mandrup, Susanne, Maechler, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312098/ https://www.ncbi.nlm.nih.gov/pubmed/32492936 http://dx.doi.org/10.3390/ijms21113982 |
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