Cargando…
The Innovative Potential of Statins in Cancer: New Targets for New Therapies
Numerous and different types of cancers possess the dysregulation of the mevalonate pathway as a common feature. Statins, traditionally applied in cardiovascular diseases to reduce lipid levels, subsequently have been discovered to exhibit anti-cancer activities also. Indeed, statins influence proli...
Autores principales: | Di Bello, Elisabetta, Zwergel, Clemens, Mai, Antonello, Valente, Sergio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312214/ https://www.ncbi.nlm.nih.gov/pubmed/32626692 http://dx.doi.org/10.3389/fchem.2020.00516 |
Ejemplares similares
-
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
por: Mazzone, Roberta, et al.
Publicado: (2017) -
Polycomb Repressive
Complex 2 Modulation through the
Development of EZH2–EED Interaction Inhibitors and EED Binders
por: Tomassi, Stefano, et al.
Publicado: (2021) -
Editorial: Chemical Innovative Approaches in Cancer Molecular Medicine and Translational Clinical Research
por: Benedetti, Rosaria, et al.
Publicado: (2020) -
Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity
por: Fioravanti, Rossella, et al.
Publicado: (2022) -
Novel 1,4-Dihydropyridines
as Specific Binders and
Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate
Hypoxia-Induced Targets in Cancer Cells
por: Zwergel, Clemens, et al.
Publicado: (2023)