Molecular profile of BRCA-mutated biliary tract cancers

INTRODUCTION: Prognosis of biliary tract cancers (BTC) remains dismal and novel treatment strategies are needed to improve survival. BRCA mutations are known to occur in BTC but their frequency and the molecular landscape in which they are observed in distinct sites of BTC remain unknown. MATERIAL A...

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Detalles Bibliográficos
Autores principales: Spizzo, Gilbert, Puccini, Alberto, Xiu, Joanne, Goldberg, Richard M, Grothey, Axel, Shields, Anthony F, Arora, Sukeshi Patel, Khushman, Moh’d, Salem, Mohamed E, Battaglin, Francesca, Baca, Yasmine, El-Deiry, Wafik S, Philip, Philip A, Nassem, Madiha, Hall, Michael, Marshall, John L, Kocher, Florian, Amann, Arno, Wolf, Dominik, Korn, W Michael, Lenz, Heinz-Josef, Seeber, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312328/
https://www.ncbi.nlm.nih.gov/pubmed/32576609
http://dx.doi.org/10.1136/esmoopen-2020-000682

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