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Sonic Hedgehog-Gli1 Signaling and Cellular Retinoic Acid Binding Protein 1 Gene Regulation in Motor Neuron Differentiation and Diseases

Cellular retinoic acid-binding protein 1 (CRABP1) is highly expressed in motor neurons. Degenerated motor neuron-like MN1 cells are engineered by introducing SOD(G93A) or AR-65Q to model degenerated amyotrophic lateral sclerosis (ALS) or spinal bulbar muscular atrophy neurons. Retinoic acid (RA)/son...

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Detalles Bibliográficos
Autores principales:	Lin, Yu-Lung, Lin, Yi-Wei, Nhieu, Jennifer, Zhang, Xiaoyin, Wei, Li-Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312406/ https://www.ncbi.nlm.nih.gov/pubmed/32527063 http://dx.doi.org/10.3390/ijms21114125

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