Cargando…

Ubiquitin Carboxyl-Terminal Hydrolases (UCHs): Potential Mediators for Cancer and Neurodegeneration

Emerging evidence suggests an inverse association between cancer and neurodegenerative diseases (NDD). Although phenotypically different, both diseases display a significant imbalance in the ubiquitination/deubiquitination processes. Therefore, we particularly investigated the expression of ubiquiti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharma, Amit, Liu, Hongde, Tobar-Tosse, Fabian, Chand Dakal, Tikam, Ludwig, Michael, Holz, Frank G., Loeffler, Karin U., Wüllner, Ullrich, Herwig-Carl, Martina C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312489/ https://www.ncbi.nlm.nih.gov/pubmed/32486284 http://dx.doi.org/10.3390/ijms21113910

Ejemplares similares

Genome organization in proximity to the BAP1 locus appears to play a pivotal role in a variety of cancers
por: Sharma, Amit, et al.
Publicado: (2020)

PPAR-Responsive Elements Enriched with Alu Repeats May Contribute to Distinctive PPARγ–DNMT1 Interactions in the Genome
por: Sharma, Amit, et al.
Publicado: (2021)

Common genetic variants associated with Parkinson’s disease display widespread signature of epigenetic plasticity
por: Sharma, Amit, et al.
Publicado: (2019)

Rice tapetum differentiation is sensitive to downregulation of OsUCH3, a ubiquitin C‐terminal hydrolase
por: Wang, Dong‐Hui, et al.
Publicado: (2023)

Ubiquitin Carboxyl-Terminal Esterase LI (UCHLI) SI8Y Polymorphism in Patients with Cataracts
por: Rudolph, Thiemo, et al.
Publicado: (2011)

Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction
por: Bishop, Paul, et al.
Publicado: (2016)

Systematic discrimination of the repetitive genome in proximity of ferroptosis genes and a novel prognostic signature correlating with the oncogenic lncRNA CRNDE in multiple myeloma
por: Qin, Jiading, et al.
Publicado: (2022)

Advanced glycation end products and protein carbonyl levels in plasma reveal sex-specific differences in Parkinson's and Alzheimer's disease
por: Sharma, Amit, et al.
Publicado: (2020)

Ubiquitin Carboxy-Terminal Hydrolase L1 (UCH-L1) is increased in cerebrospinal fluid and plasma of patients after epileptic seizure
por: Mondello, Stefania, et al.
Publicado: (2012)

Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma
por: Seliger, Barbara, et al.
Publicado: (2009)

Overexpression of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in boys with cryptorchidism
por: Toliczenko-Bernatowicz, Dorota, et al.
Publicado: (2018)

SARS-CoV-2 attachment to host cells is possibly mediated via RGD-integrin interaction in a calcium-dependent manner and suggests pulmonary EDTA chelation therapy as a novel treatment for COVID 19
por: Dakal, Tikam Chand
Publicado: (2021)

Antigenic sites in SARS-CoV-2 spike RBD show molecular similarity with pathogenic antigenic determinants and harbors peptides for vaccine development
por: Dakal, Tikam Chand
Publicado: (2021)

Ubiquitin C-Terminal Hydrolase-L1 (UCH-L1) in Prediction of Computed Tomography Findings in Traumatic Brain Injury; a Meta-Analysis
por: Ramezani, Fatemeh, et al.
Publicado: (2018)

Mutational Landscape of the BAP1 Locus Reveals an Intrinsic Control to Regulate the miRNA Network and the Binding of Protein Complexes in Uveal Melanoma
por: Sharma, Amit, et al.
Publicado: (2019)

Ubiquitin carboxyl-terminal hydrolases are required for period maintenance of the circadian clock at high temperature in Arabidopsis
por: Hayama, Ryosuke, et al.
Publicado: (2019)

Pivotal Role of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) in Uterine Leiomyoma
por: Suzuki, Tomoo, et al.
Publicado: (2023)

Overexpression of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) delays Alzheimer's progression in vivo
por: Zhang, Mingming, et al.
Publicado: (2014)

Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's Disease
por: Öhrfelt, Annika, et al.
Publicado: (2016)

High-level expression of active recombinant ubiquitin carboxyl-terminal hydrolase of Drosophila melanogaster in Pichia pastoris
por: Jin, Feng-liang, et al.
Publicado: (2009)

Ubiquitin Carboxyl-Terminal Hydrolases and Human Malignancies: The Novel Prognostic and Therapeutic Implications for Head and Neck Cancer
por: Rong, Chao, et al.
Publicado: (2021)

Contrasting Patterns of rDNA Homogenization within the Zygosaccharomyces rouxii Species Complex
por: Chand Dakal, Tikam, et al.
Publicado: (2016)

The expression and clinical value of ubiquitin carboxyl-terminal hydrolase L1 in the blood of neonates with hypoxic ischemic encephalopathy
por: Zeng, Shuying, et al.
Publicado: (2021)

The Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) C Terminus Plays a Key Role in Protein Stability, but Its Farnesylation Is Not Required for Membrane Association in Primary Neurons
por: Bishop, Paul, et al.
Publicado: (2014)

Modelling the Role of UCH-L1 on Protein Aggregation in Age-Related Neurodegeneration
por: Proctor, Carole J., et al.
Publicado: (2010)

Proteomic Analysis of Hippocampus in a Mouse Model of Depression Reveals Neuroprotective Function of Ubiquitin C-terminal Hydrolase L1 (UCH-L1) via Stress-induced Cysteine Oxidative Modifications
por: Choi, Jung-Eun, et al.
Publicado: (2018)

Changes and significance of serum ubiquitin carboxyl-terminal hydrolase L1 and glial fibrillary acidic protein in patients with glioma
por: Zhu, Qing-Hua, et al.
Publicado: (2023)

Ubiquitin C-Terminal Hydrolase L1 in Tumorigenesis
por: Hurst-Kennedy, Jennifer, et al.
Publicado: (2012)

Towards a Central Role of ISL1 in the Bladder Exstrophy–Epispadias Complex (BEEC): Computational Characterization of Genetic Variants and Structural Modelling
por: Sharma, Amit, et al.
Publicado: (2018)

Sex-Determination System in the Diploid Yeast Zygosaccharomyces sapae
por: Solieri, Lisa, et al.
Publicado: (2014)

Mechanistic Basis of Antimicrobial Actions of Silver Nanoparticles
por: Dakal, Tikam Chand, et al.
Publicado: (2016)

MicroRNA-1288 promotes cell proliferation of human glioblastoma cells by repressing ubiquitin carboxyl-terminal hydrolase CYLD expression
por: Yin, Jun, et al.
Publicado: (2017)

Ubiquitin carboxyl-terminal hydrolase isozyme L5 inhibits human glioma cell migration and invasion via downregulating SNRPF
por: Ge, Jiafeng, et al.
Publicado: (2017)

Circulating Ubiquitin Carboxyl Terminal Hydrolase L1 and Neuroglobin Levels in Traumatic Spinal Cord Injuries: Relation to Severity and Outcomes
por: Abuhamdah, Sawsan, et al.
Publicado: (2022)

Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis
por: Nan, Ling, et al.
Publicado: (2016)

Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation
por: Ummanni, Ramesh, et al.
Publicado: (2011)

Ubiquitin carboxyl‐terminal hydrolase L1 promotes hypoxia‐inducible factor 1‐dependent tumor cell malignancy in spheroid models
por: Li, Xuebing, et al.
Publicado: (2019)

Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression
por: Kwan, Suet-Ying, et al.
Publicado: (2020)

Characterization of the Ubiquitin C-Terminal Hydrolase and Ubiquitin-Specific Protease Families in Rice (Oryza sativa)
por: Wang, Dong-Hui, et al.
Publicado: (2018)

Drosophila Ubiquitin C-Terminal Hydrolase Knockdown Model of Parkinson’s Disease
por: Tran, Hiep H., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_prmqrq5dqags3h9sm39jjg2a20