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Ibrutinib in Gynecological Malignancies and Breast Cancer: A Systematic Review

Ibrutinib is an orally available, small-molecule tyrosine kinase inhibitor. Its main purpose is to inhibit Bruton’s tyrosine kinase (BTK), an enzyme that is crucial in B cell development. It is FDA approved for the treatment of certain hematological malignancies. Several promising off-target drug ef...

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Detalles Bibliográficos
Autores principales:	Metzler, Julian Matthias, Burla, Laurin, Fink, Daniel, Imesch, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312555/ https://www.ncbi.nlm.nih.gov/pubmed/32532074 http://dx.doi.org/10.3390/ijms21114154

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