Vitamin E Blocks Connexin Hemichannels and Prevents Deleterious Effects of Glucocorticoid Treatment on Skeletal Muscles

Glucocorticoids are frequently used as anti-inflammatory and immunosuppressive agents. However, high doses and/or prolonged use induce undesired secondary effects such as muscular atrophy. Recently, de novo expression of connexin43 and connexin45 hemichannels (Cx43 HCs and Cx45 HCs, respectively) ha...

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Detalles Bibliográficos
Autores principales: Balboa, Elisa, Saavedra, Fujiko, Cea, Luis A., Ramírez, Valeria, Escamilla, Rosalba, Vargas, Aníbal A., Regueira, Tomás, Sáez, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312599/
https://www.ncbi.nlm.nih.gov/pubmed/32521774
http://dx.doi.org/10.3390/ijms21114094

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