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The Role of P2X7 Purinergic Receptors in the Renal Inflammation Associated with Angiotensin II-Induced Hypertension

Purinergic receptors play a central role in the renal pathophysiology of angiotensin II-induced hypertension, since elevated ATP chronically activates P2X7 receptors in this model. The changes induced by the P2X antagonist Brilliant blue G (BBG) in glomerular hemodynamics and in tubulointerstitial i...

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Detalles Bibliográficos
Autores principales: Bautista-Pérez, Rocio, Pérez-Méndez, Oscar, Cano-Martínez, Agustina, Pacheco, Ursino, Santamaría, José, Rodríguez-Sámano, Fernando, Rodríguez-Iturbe, Bernardo, Navar, L. Gabriel, Franco, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312644/
https://www.ncbi.nlm.nih.gov/pubmed/32516946
http://dx.doi.org/10.3390/ijms21114041