Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling Are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes)

Vertebral endplate bone marrow lesions, visualized on magnetic resonance imaging (MRI) as Modic changes (MC), are associated with chronic low back pain (cLBP). Since guidelines recommend against routine spinal MRI for cLBP in primary care, MC may be underdiagnosed. Serum biomarkers for MC would allo...

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Detalles Bibliográficos
Autores principales: Dudli, Stefan, Ballatori, Alexander, Bay-Jensen, Anne-Christine, McCormick, Zachary L., O’Neill, Conor W., Demir-Deviren, Sibel, Krug, Roland, Heggli, Irina, Juengel, Astrid, Karppinen, Jaro, Brunner, Florian, Farshad, Mazda, Distler, Oliver, Lotz, Jeffrey C., Fields, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312719/
https://www.ncbi.nlm.nih.gov/pubmed/32471173
http://dx.doi.org/10.3390/ijms21113791

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