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Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order

Pulsatility index (PI) values in a fetal middle cerebral artery (MCA) were compared in no-risk pregnancies to examine the differences related to auditory stimulation test and pregnancy order. The study included 196 women with no-risk pregnancies selected from the database of more than 1000 pregnant...

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Autores principales: Jeličić, Ljiljana, Janković, Svetlana, Sovilj, Mirjana, Adamović, Tatjana, Bogavac, Ivana, Gavrilović, Aleksandar, Subotić, Miško
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312760/
https://www.ncbi.nlm.nih.gov/pubmed/32485789
http://dx.doi.org/10.3390/ijms21113855
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author Jeličić, Ljiljana
Janković, Svetlana
Sovilj, Mirjana
Adamović, Tatjana
Bogavac, Ivana
Gavrilović, Aleksandar
Subotić, Miško
author_facet Jeličić, Ljiljana
Janković, Svetlana
Sovilj, Mirjana
Adamović, Tatjana
Bogavac, Ivana
Gavrilović, Aleksandar
Subotić, Miško
author_sort Jeličić, Ljiljana
collection PubMed
description Pulsatility index (PI) values in a fetal middle cerebral artery (MCA) were compared in no-risk pregnancies to examine the differences related to auditory stimulation test and pregnancy order. The study included 196 women with no-risk pregnancies selected from the database of more than 1000 pregnant women divided into two groups. Group 1 consisted of 98 nulliparous women (C1 = 98) and Group 2 consisted of 98 parous women (C2 = 98). All pregnant women were of comparable age and fetal gestational age (GA) when MCA-PI values were recorded. Measurements of PI values in fetal MCA were obtained before and immediately after the application of fetal auditory stimulation test. The MCA-PI measuring was conducted in the period between the 36th and the 41st week of GA. The results showed that PI baseline values and PI values after defined auditory stimulation were significantly different when measured in nulliparous women compared to parous women (p = 0.001; p = 0.003, respectively), while no group differences were observed in relative PI value changes due to auditory stimulation. These findings suggest that hemodynamic changes in fetal MCA caused by defined auditory stimulation measured by PI value changes may be valuable in the assessment of fetal auditory perception functionality and its development.
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spelling pubmed-73127602020-06-26 Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order Jeličić, Ljiljana Janković, Svetlana Sovilj, Mirjana Adamović, Tatjana Bogavac, Ivana Gavrilović, Aleksandar Subotić, Miško Int J Mol Sci Article Pulsatility index (PI) values in a fetal middle cerebral artery (MCA) were compared in no-risk pregnancies to examine the differences related to auditory stimulation test and pregnancy order. The study included 196 women with no-risk pregnancies selected from the database of more than 1000 pregnant women divided into two groups. Group 1 consisted of 98 nulliparous women (C1 = 98) and Group 2 consisted of 98 parous women (C2 = 98). All pregnant women were of comparable age and fetal gestational age (GA) when MCA-PI values were recorded. Measurements of PI values in fetal MCA were obtained before and immediately after the application of fetal auditory stimulation test. The MCA-PI measuring was conducted in the period between the 36th and the 41st week of GA. The results showed that PI baseline values and PI values after defined auditory stimulation were significantly different when measured in nulliparous women compared to parous women (p = 0.001; p = 0.003, respectively), while no group differences were observed in relative PI value changes due to auditory stimulation. These findings suggest that hemodynamic changes in fetal MCA caused by defined auditory stimulation measured by PI value changes may be valuable in the assessment of fetal auditory perception functionality and its development. MDPI 2020-05-29 /pmc/articles/PMC7312760/ /pubmed/32485789 http://dx.doi.org/10.3390/ijms21113855 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jeličić, Ljiljana
Janković, Svetlana
Sovilj, Mirjana
Adamović, Tatjana
Bogavac, Ivana
Gavrilović, Aleksandar
Subotić, Miško
Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
title Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
title_full Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
title_fullStr Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
title_full_unstemmed Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
title_short Fetal Middle Cerebral Artery Pulsatility Index in No-Risk Pregnancies: Effects of Auditory Stimulation and Pregnancy Order
title_sort fetal middle cerebral artery pulsatility index in no-risk pregnancies: effects of auditory stimulation and pregnancy order
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312760/
https://www.ncbi.nlm.nih.gov/pubmed/32485789
http://dx.doi.org/10.3390/ijms21113855
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