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Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study

Background: The aim of this study was to estimate the frequency of functional gastrointestinal disorders (FGIDs) in infants aged up to 12 months according to the new ROME IV criteria defining these disorders, and to describe the management of FGIDs in France. Methods: This French non-interventional,...

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Autores principales: Campeotto, Florence, Barbaza, Marie-Odile, Hospital, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312775/
https://www.ncbi.nlm.nih.gov/pubmed/32517046
http://dx.doi.org/10.3390/ijerph17114031
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author Campeotto, Florence
Barbaza, Marie-Odile
Hospital, Veronique
author_facet Campeotto, Florence
Barbaza, Marie-Odile
Hospital, Veronique
author_sort Campeotto, Florence
collection PubMed
description Background: The aim of this study was to estimate the frequency of functional gastrointestinal disorders (FGIDs) in infants aged up to 12 months according to the new ROME IV criteria defining these disorders, and to describe the management of FGIDs in France. Methods: This French non-interventional, cross-sectional, and multicenter study was conducted among private-outpatient physicians who each included four consecutive patients aged up to 12 months. The frequency of FGIDs was described using the ROME IV criteria versus clinicians’ diagnosis. The characteristics of infants with and without FGID were compared, and the management of the FGIDs was described. Results: In the 1722 infants analyzed, the following frequencies were observed according to the ROME IV criteria versus the physicians’ diagnosis: regurgitation 41% versus 45%; colic 18% versus 30%; constipation 9% versus 19%; diarrhea 3% versus 8%. Of note, FGID infants were less frequently exclusively breastfeeding at the maternity hospital (p < 0.001), were introduced to cow’s milk earlier after leaving the maternity hospital (p < 0.001), and more frequently had symptoms suggestive of cow’s milk protein allergy (p < 0.001). Physicians frequently recommended an adapted infant formula (in 77% to 82% of cases depending on the FGID diagnosed) and prescribed a specific treatment in 51% to 66% of infants (probiotics: 35% to 64%). Conclusions: This real-world study confirms the high frequency of FGIDs in infants in France, and provides new information regarding the characteristics of FGID infants.
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spelling pubmed-73127752020-06-26 Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study Campeotto, Florence Barbaza, Marie-Odile Hospital, Veronique Int J Environ Res Public Health Article Background: The aim of this study was to estimate the frequency of functional gastrointestinal disorders (FGIDs) in infants aged up to 12 months according to the new ROME IV criteria defining these disorders, and to describe the management of FGIDs in France. Methods: This French non-interventional, cross-sectional, and multicenter study was conducted among private-outpatient physicians who each included four consecutive patients aged up to 12 months. The frequency of FGIDs was described using the ROME IV criteria versus clinicians’ diagnosis. The characteristics of infants with and without FGID were compared, and the management of the FGIDs was described. Results: In the 1722 infants analyzed, the following frequencies were observed according to the ROME IV criteria versus the physicians’ diagnosis: regurgitation 41% versus 45%; colic 18% versus 30%; constipation 9% versus 19%; diarrhea 3% versus 8%. Of note, FGID infants were less frequently exclusively breastfeeding at the maternity hospital (p < 0.001), were introduced to cow’s milk earlier after leaving the maternity hospital (p < 0.001), and more frequently had symptoms suggestive of cow’s milk protein allergy (p < 0.001). Physicians frequently recommended an adapted infant formula (in 77% to 82% of cases depending on the FGID diagnosed) and prescribed a specific treatment in 51% to 66% of infants (probiotics: 35% to 64%). Conclusions: This real-world study confirms the high frequency of FGIDs in infants in France, and provides new information regarding the characteristics of FGID infants. MDPI 2020-06-05 2020-06 /pmc/articles/PMC7312775/ /pubmed/32517046 http://dx.doi.org/10.3390/ijerph17114031 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Campeotto, Florence
Barbaza, Marie-Odile
Hospital, Veronique
Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study
title Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study
title_full Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study
title_fullStr Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study
title_full_unstemmed Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study
title_short Functional Gastrointestinal Disorders in Outpatients Aged up to 12 Months: A French Non-Interventional Study
title_sort functional gastrointestinal disorders in outpatients aged up to 12 months: a french non-interventional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312775/
https://www.ncbi.nlm.nih.gov/pubmed/32517046
http://dx.doi.org/10.3390/ijerph17114031
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