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Progesterone Attenuates Stress-Induced NLRP3 Inflammasome Activation and Enhances Autophagy Following Ischemic Brain Injury

NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome inhibition and autophagy induction attenuate inflammation and improve outcome in rodent models of cerebral ischemia. However, the impact of chronic stress on NLRP3 inflammasome and autophagic response to ischemia remains unknown. Proge...

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Detalles Bibliográficos
Autores principales:	Espinosa-Garcia, Claudia, Atif, Fahim, Yousuf, Seema, Sayeed, Iqbal, Neigh, Gretchen N., Stein, Donald G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312827/ https://www.ncbi.nlm.nih.gov/pubmed/32466385 http://dx.doi.org/10.3390/ijms21113740

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